REGEHR LAB
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DYNAMIC
CLAMP
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We use dynamic clamp to
determine how the properties of synapses
interact with voltage gated conductances to
determine the computations performed by cells.
This approach allows us to mimic synaptic inputs
to cells by using synaptic conductances to
trigger spiking. In this example MF synapases
are activated at different frequencies and the
resulting input-output transformation is
determined.
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| WADE
REGEHR
DEPARTMENT OF NEUROBIOLOGY
HARVARD MEDICAL SCHOOL |